Predictive role ofXRCC5/XRCC6genotypes in digestive system cancers
نویسندگان
چکیده
منابع مشابه
Cathepsins in digestive cancers
Cathepsins are lysosomal peptidases belonging to the papain family, and based on their catalytic sites, these enzymes can be divided into serine, cysteine and aspartic proteases. The studies conducted to date have identified, 15 types of cathepsins that are widely distributed in intracellular and extracellular spaces. These proteases participate in various pathological activities, including the...
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Thyroid hormones play a critical role in the growth and development of the alimentary tract in vertebrates. Their effects are mediated by nuclear receptors as well as the cell surface receptor integrin αVβ3. Systemic thyroid hormone levels are controlled via activation and deactivation by iodothyronine deiodinases in the liver and other tissues. Given that thyroid hormone signaling has been cha...
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Gallstones and cholecystectomy may be related to digestive system cancer through inflammation, altered bile flux, and changes in metabolic hormone levels. Although gallstones are recognized causes of gallbladder cancer, associations with other cancers of the digestive system are poorly established. We used the Surveillance, Epidemiology, and End Results (SEER)-Medicare linked database (1992-200...
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Digestive system cancers-those of the esophagus, stomach, small intestine, colon-rectum, liver, and pancreas-are highly related to genetics and lifestyle. Most are considered highly mortal due to the frequency of late diagnosis, usually in advanced stages, caused by the absence of symptoms or masked by other pathologies. Different tools are being investigated in the search of a more precise dia...
متن کاملDigestive cancers in Morocco: Fez-Boulemane region
INTRODUCTION To describe the epidemiological and pathological aspects of gastrointestinal cancers in Fez-Boulemane. METHODS This was a retrospective descriptive study of 1120 gastrointestinal cancers diagnosed between 2004 and 2010 in the department of Pathology of Hassan II University Hospital in Fez Morocco. RESULTS The average age of our patients was 53 years with a male predominance in ...
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ژورنال
عنوان ژورنال: World Journal of Gastrointestinal Oncology
سال: 2011
ISSN: 1948-5204
DOI: 10.4251/wjgo.v3.i12.175